The 3D structure of the drug-protein complex can precisely reveal how a drug binds to and acts on a target protein. These details are useful in guiding the design and modification of more effective drug candidates. Structure-based drug design (SBDD) and fragment-based drug discovery (FBDD) have become increasingly powerful methods for drug research and development.

Advantages of drug design and screening based on the three-dimensional atomic structure of proteins:

1.Obtain the binding mode and interaction between drugs and target proteins;

2.Guide on how to design/modify more effective new drug molecules;

3.AlpHelix focuses on structural biology of membrane protein using crystallography and cryo-EM techniques. We are committed to providing one-stop structural biology technology services for global pharmaceutical companies and biotechnology companies, from drug target preparation to preclinical candidate compound screening. Using our advanced technology platform, we assist global customers with efficient drug screening and revealing action mechanisms, structure-based drug design, and fragment-based drug discovery, thereby accelerating innovation while reducing costs.